Molecular Biology Laboratory

The Molecular Biology Laboratory (BIOMOL) integrates all the basic skills necessary for studies at the level of DNA, RNA and proteins, as well as for studies involving the determination of respiratory parameters. Ongoing research works are divided into four lines funded by different projects. The main objective is the study of the response of plants to stress conditions, mostly stresses abiotic, being the research focused on the study of Transcriptomas and its association with the existing variability in the level and phenotype (plant) and Genome (identification of functional polymorphisms).

Responsável: Hélia Cardoso []


Hélia Cardoso – Post-Doc Researcher (SFRH/BPD/109849/2015)
Isabel Velada – Post-Doc Researcher, felowship in project OLEAVALOR
Maria Catarina Campos – Post-Doc Researcher (SFRH/BPD/108734/2015)

Contactos e Horário

Telemóvel: +351 963147533,


Horário: 9:30 am – 5:30 pm

The lab was established different protocols of collaboration with international companies, belonging to the sector of seed production in order to validate a methodology that might be used as a service for phenotyping associated with plant breeding.

Line 1: Forecasting of plant growth performance under different temperatures by monitoring parameters associated with breathing

This line of research is supported by the LIVESEED project (Improve performance of organic agriculture by boosting organic seed and plant breeding efforts across Europe, H2020-CP-STAGE-RIA-CSA-727230-2, responsible Birgit Arnholdt-Schmitt) and for a Bilateral cooperation Portugal-India funded by FCT, entitled "Alternative oxidase-a tool to increase biomass productivity under temperature and flooding stress" (R&D Joint Projects India-Portugal 2017 – 2019, responsible Birgit Arnholdt-Schmitt).

For consultation of publications associated with this line of research and collaborations established with companies and research institutes consult

Researchers of the BIOMOL involved: Birgit Arnholdt-Schmitt (, Elisa Santos Macedo .

Line 2: Study of the molecular mechanisms involved in the rooting adventitious of Oliveira (Olea Europaea L.).

This line of research is funded by the project "OLEAVALOR- Valorization of the varieties of Portuguese olive tree (ALT20-03-0145-Feder-000014, responsible Prof. Augusto Peixe).

Researchers of the BIOMOL involved: Hélia Cardoso (, Isabel Velada (

Line 3: Study of the molecular mechanisms of plants in response to extrinsic stimuli, both biotics and abiotic.

It has been verified that the association of plants with fungi fungi mycorrhizal can enhance both the absorption of nutrients as well as the protection from stresses such as existing metals in excess in the soil. These studies are intended to identify which plant genes are involved in responding to the plants that induce the plant's bioprotection, and how these genes are regulated by epigenetic mechanisms such as microRNAs or DNA methylation. A greater understanding between beneficial plant/fungus associations mycorrhizal can lead to better management of agricultural systems. This line of research is funded by the project "Improving the production of pastures in acid soils in the assembled: chemical and biological approach" (ALT20-03-0145-Feder-000039, responsible Mário de Carvalho).

BIOMOL investigators involved: Catarina Campos (

Line 4: Establishment of a methodology that allows the discrimination of varieties used in the production of olive oil

The authenticity of extra virgin olive oils, in the geographical and varietal aspect is the main objective of the project that finances this line of research. The genomic approach aims to analyze the DNA extracted from the olive oil and the definition of molecular markers that allow to identify each of the varieties considered in its production. This approach seeks to obtain a molecular signature for each of the varieties and provide a useful tool for the analysis of oil in the sense of screening for fraud (by identifying its varietal composition), and still be used for The certification of varietal olive oils. This line of research is funded by the project "PRO30-a Ómica approach applied to Portuguese oils" (PTDC/AGR-PRO/2003/2014, responsible Maria João goata).

BIOMOL investigators involved: Andreia Dias (, Hélio Cardoso (

The Molecular Biology Laboratory supports the practice of the degree course in Biotechnology and a master's degree in agricultural engineering and supports implementation research to graduate level, master's, PhD and post doc

The Molecular Biology Laboratory is also involved in scientific activities targeted to secondary school students, and collaborate in the Science Alive program.